Crp prov hund

C-Reactive Protein in Dogs: A Review for the General Practitioner

Dr. Oberholtzer earned her DVM degree from the University of Minnesota. This review was written during her rotating internship at the Texas A&M University Small Animal Teaching Hospital. She is currently in the first year of her internal medicine residency at the University of Minnesota. Her areas of interest include gastroenterology, immune-mediated diseases, and infectious diseases.

Read Articles Written by Sydney Oberholtzer

Audrey Cook

BVM&S, MSc VetEd, MRCVS, DACVIM (SAIM), DECVIM-CA, DABVP (Feline)

Dr. Audrey Cook is a graduate of the University of Edinburgh. She completed an internship at NCSU and a residency in internal medicine at UC Davis. She is a Diplomate of the American and European Colleges of Veterinary Internal Medicine, and is one of the few internists with additional board certification in Feline Practice. After a decade in private referral practice, Dr. Cook joined the faculty at Texas A&M College of Veterinary Medicine. She is currently Professor and Chief of the Internal Medicine Service. Her clinical interests include canine and feline endocrinology and gastroente

  • crp prov hund

    • cCRP test

    Canine c-reactive protein

    About the parameter



    C-reactive protein (CRP) is an acute phase protein. The serum level of CRP rises significantly in animals that suffer from different types of infection or inflammation, correlating with degree and activity of the causative disease. Measurements of serum CRP are used to aid the evaluation of the inflammation associated with infection, tissues damage and other clinical disorders.

    Increased levels of CRP were described in dogs that suffered from pneumonia, pyometra, pancreatitis, parvovirus infection or traumatism. Dogs with an increased number of leukocytes had significantly higher CRP levels than dogs with noninflammatory leukograms. Increased CRP levels were also found in dogs with arthritis, thrombophlebitis or procitis. Moreover, they were observed in dogs infected with Bordetella bronchiseptica or Ehrlichia canis. This in-vitro test kit is designed to measure canine CRP in serum and plasma.

    Overview

    Sample material

    Recommended sample material is canine serum, canine heparinized plasma or canine EDTA plasma. Sample stability testing showed that canine CRP (in serum) was stable for 14 days
    at 2 &#; 8 °C.

    CRP is a major acute phase protein in dogs and the measurement of canine CRP is therefore important in diagnosis and treatment of inflammatory disorders in dogs. The Gentian Canine CRP Immunoassay fryst vatten specific for dogs since the antibodies are produced by immunising hens with a purified canine CRP antigen.

    Canine CRP in the clinical setting

    Canine CRP can not only be analysed to detect and quantitate the grad of systemic inflammation, but also to monitor the treatment response of the patient dog. If the cause of inflammation fryst vatten successfully removed, the serum CRP levels drop rapidly due to its short half-life (about 19 hours)1,4. The levels of CRP will thus directly reflect the extent of inflammation.

    Compared to classical inflammation markers, such as WBC (white blood cell count) and ESR (erythrocyte sedimentation rate), CRP has been shown to have higher sensitivity and better monitoring abilities. In therapy monitoring, CRP levels drop more rapidly compared to WBS and ESR when the patient dog receives efficient treatment8.

    Due to the fast expression of canine CRP in cases of inflammation, CRP is also often used for prognostic purposes. CPR levels ocean